IL-8

1ICW, 1IKL, 1IKM, 1IL8, 1ILP, 1ILQ, 1QE6, 1ROD, 2IL8, 3IL8· protein binding· response to molecule of bacterial origin · cellular component movement · inflammatory response · immune response · activation of signaling protein activity involved in unfolded protein response · cell cycle arrest · signal transduction · G-protein coupled receptor signaling pathway · negative regulation of cell proliferation · calcium-mediated signaling · regulation of cell adhesion · neutrophil chemotaxis · endoplasmic reticulum unfolded protein response · receptor internalization · response to endoplasmic reticulum stress · intracellular signal transduction · neutrophil activation · cellular protein metabolic process · cellular response to fibroblast growth factor stimulus · regulation of retroviral genome replication · negative regulation of G-protein coupled receptor protein signaling pathway · embryonic digestive tract development · induction of positive chemotaxis · cellular response to lipopolysaccharide · cellular response to interleukin-1 · cellular response to tumor necrosis factor白细胞介素-8（英语：Interleukin-8，简称为白介素-8或IL-8，亦称为趋化因子CXCL8）是巨噬细胞和上皮细胞等分泌的细胞因子。白细胞介素-8结合趋化因子受体白细胞介素-8受体α(IL8RA, 又叫CXCR1)和白细胞介素-8受体β(IL8RB, 又叫CXCR2)而对嗜中性粒细胞(neutrophils)有细胞趋化作用而实现其对炎症反应的调节。 白细胞介素-8还有很强的促血管生成作用。白细胞介素-8在小支气管炎 和囊性纤维化 的发病中起重要作用。