过氧化物酶体增殖物活化受体γ

✍ dations ◷ 2025-04-11 05:30:43 #人类蛋白质,核受体

1FM6, 1FM9, 1I7I, 1K74, 1KNU, 1NYX, 1PRG, 1RDT, 1WM0, 1ZEO, 1ZGY, 2ATH, 2F4B, 2FVJ, 2G0G, 2G0H, 2GTK, 2HFP, 2HWQ, 2HWR, 2I4J, 2I4P, 2I4Z, 2OM9, 2P4Y, 2POB, 2PRG, 2Q59, 2Q5P, 2Q5S, 2Q61, 2Q6R, 2Q6S, 2Q8S, 2QMV, 2VSR, 2VST, 2VV0, 2VV1, 2VV2, 2VV3, 2VV4, 2XKW, 2YFE, 2ZK0, 2ZK1, 2ZK2, 2ZK3, 2ZK4, 2ZK5, 2ZK6, 2ZNO, 2ZVT, 3ADS, 3ADT, 3ADU, 3ADV, 3ADW, 3ADX, 3AN3, 3AN4, 3B0Q, 3B0R, 3B1M, 3B3K, 3BC5, 3CDP, 3CDS, 3CS8, 3CWD, 3D6D, 3DZU, 3DZY, 3E00, 3ET0, 3ET3, 3FEJ, 3FUR, 3G9E, 3GBK, 3H0A, 3HO0, 3HOD, 3IA6, 3K8S, 3KMG, 3LMP, 3NOA, 3OSI, 3OSW, 3PBA, 3PO9, 3PRG, 3QT0, 3R5N, 3R8A, 3R8I, 3S9S, 3SZ1, 3T03, 3TY0, 3U9Q, 3V9T, 3V9V, 3V9Y, 3VJH, 3VJI, 3VN2, 3VSO, 3VSP, 4A4V, 4A4W, 4E4K, 4E4Q, 4EM9, 4EMA, 4F9M, 4FGY, 4PRG

· DNA binding
· chromatin binding
· sequence-specific DNA binding transcription factor activity
· steroid hormone receptor activity
· ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
· prostaglandin receptor activity
· protein binding
· drug binding
· zinc ion binding
· enzyme binding
· ligand-dependent nuclear receptor transcription coactivator activity
· activating transcription factor binding
· sequence-specific DNA binding
· transcription regulatory region DNA binding
· retinoid X receptor binding

· nucleoplasm

· placenta development
· negative regulation of acute inflammatory response
· transcription initiation from RNA polymerase II promoter
· lipid metabolic process
· induction of apoptosis
· activation of cysteine-type endopeptidase activity involved in apoptotic process
· signal transduction
· heart development
· response to nutrient
· regulation of blood pressure
· response to cold
· gene expression
· negative regulation of macrophage derived foam cell differentiation
· negative regulation of receptor biosynthetic process
· negative regulation of cholesterol storage
· negative regulation of sequestering of triglyceride
· long-chain fatty acid transport
· fatty acid oxidation
· monocyte differentiation
· negative regulation of cell growth
· epithelial cell differentiation
· response to caffeine
· organ regeneration
· response to retinoic acid
· cellular response to insulin stimulus
· response to vitamin A
· response to lipid
· peroxisome proliferator activated receptor signaling pathway
· response to drug
· glucose homeostasis
· lipoprotein transport
· response to estrogen stimulus
· innate immune response
· cell fate commitment
· positive regulation of fat cell differentiation
· low-density lipoprotein particle receptor biosynthetic process
· negative regulation of transcription, DNA-dependent
· positive regulation of transcription, DNA-dependent
· positive regulation of transcription from RNA polymerase II promoter
· positive regulation of fatty acid oxidation
· cell maturation
· negative regulation of smooth muscle cell proliferation
· positive regulation of oligodendrocyte differentiation
· white fat cell differentiation
· brown fat cell differentiation
· positive regulation of sequence-specific DNA binding transcription factor activity
· negative regulation of telomerase activity
· lipid homeostasis
· response to low-density lipoprotein particle stimulus
· negative regulation of interferon-gamma-mediated signaling pathway
· regulation of cholesterol transporter activity

过氧化物酶体增殖物活化受体γ(Peroxisome proliferator-activated receptor gamma ,缩写为PPAR-γ或PPARG),也称胰岛素增敏剂受体(glitazone receptor),或 NR1C3(意为核受体第一亚科C集团第3号,nuclear receptor subfamily 1, group C, member 3)是一种位于人类染色体上的二型核受体,由PPARG基因编码。对脂肪细胞和胰岛素有重要的作用,是治疗糖尿病的研究对象之一。

相关

  • 四氟硼酸二茂铁四氟硼酸二茂铁是一种有机金属化合物,化学式为BF4。这种盐由+阳离子和氟硼酸根阴离子(BF4-)组成。性质类似的六氟磷酸盐也是一种受欢迎的试剂。阳离子往往缩写成Fc+或(Cp2Fe)+
  • 玛雅文明玛雅文明(Mayan),是古代分布于今墨西哥东南部、危地马拉、洪都拉斯、萨尔瓦多和伯利兹5个国家的丛林文明。虽然处于新石器时代,惟在天文学、数学、农业、艺术及文字等方面都有极
  • 小丘广场小丘广场(法语:Place du Tertre)是法国巴黎的一个广场,位于巴黎十八区蒙马特,距离圣心堂与狡兔酒吧(Lapin Agile)不远。小丘广场经常聚集许多艺术家,也是巴黎著名的景点之一。毕加索
  • 聚焦聚焦可以指:
  • 鸸鹋Dromiceius novaehollandiae鸸鹋(学名:Dromaius novaehollandiae、拼音:ér miáo,注音:ㄦˊ ㄇㄧㄠˊ,音同“儿苗”),是现存世上除了鸵鸟以外最大的鸟类,为鸸鹋属唯一的物种。由于仅
  • 化石纪录化石是存留在岩石中的古生物遗体、遗物或生活痕迹,最常见的是骸骨和贝壳等。研究化石可以了解生物的演化并能帮助确定地层的年代。保存在地壳的岩石中的古动物或古植物的遗体
  • 猴脑猴脑是亚洲珍贵的传统食材,八珍之一。猴脑据传多以生食,吃猴脑的餐桌中间开一洞,其大小恰好可穿进猴头。待猴头伸出桌面时,将活猴的头骨击碎,再淋上热油,用银勺挖出脑髓食用。然而
  • 斛(拼音:hú,注音:ㄏㄨˊ,音同“胡”)是古代容积单位。唐朝之前,斛为民间对石的俗称,1斛=1石,1石=10斗。汉朝许慎的《说文解字》:“斛,十斗也。”从宋朝开始,改为1斛 = 5斗(今制十斗为一
  • 中密歇根大学中密歇根州立大学 (Central Michigan University "CMU") 是美国的一所州立大学,位于 密歇根州芒特普莱森特(英语:Mount Pleasant)。有将近27,000名学生,其中将近20,000人为大学部
  • 特瓦族特瓦族,也被称为巴特瓦族,属于矮人,是非洲大湖地区记录中最古老的种族。族群分布在卢旺达、布隆迪、乌干达和刚果民主共和国东部。2000年,普查到大约有8万人,作为在这些国家重要