PML

✍ dations ◷ 2025-06-06 15:40:18 #PML
1BOR· transcription coactivator activity · protein binding · zinc ion binding · ubiquitin protein ligase binding · SUMO binding · protein homodimerization activity · SMAD binding · protein heterodimerization activity· nucleoplasm · nucleolus · cytoplasm · cytosol · nuclear matrix · PML body · early endosome membrane · nuclear membrane· regulation of protein phosphorylation · positive regulation of defense response to virus by host · transcription, DNA-templated · regulation of transcription, DNA-templated · protein complex assembly · protein targeting · apoptotic process · activation of cysteine-type endopeptidase activity involved in apoptotic process · DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest · cell cycle arrest · transforming growth factor beta receptor signaling pathway · common-partner SMAD protein phosphorylation · SMAD protein import into nucleus · negative regulation of cell proliferation · intrinsic apoptotic signaling pathway in response to DNA damage · intrinsic apoptotic signaling pathway in response to oxidative stress · response to UV · response to gamma radiation · regulation of calcium ion transport into cytosol · viral process · negative regulation of angiogenesis · cytokine-mediated signaling pathway · myeloid cell differentiation · negative regulation of cell growth · PML body organization · positive regulation of histone deacetylation · negative regulation of telomere maintenance via telomerase · endoplasmic reticulum calcium ion homeostasis · circadian regulation of gene expression · negative regulation of translation in response to oxidative stress · response to cytokine · regulation of circadian rhythm · intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator · entrainment of circadian clock by photoperiod · proteasome-mediated ubiquitin-dependent protein catabolic process · innate immune response · cell fate commitment · regulation of MHC class I biosynthetic process · negative regulation of transcription, DNA-templated · negative regulation of mitotic cell cycle · retinoic acid receptor signaling pathway · protein stabilization · maintenance of protein location in nucleus · defense response to virus · negative regulation of telomerase activity · positive regulation of apoptotic process involved in mammary gland involution · interferon-gamma-mediated signaling pathway · branching involved in mammary gland duct morphogenesis · intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress · cellular response to interleukin-4 · cellular senescence · extrinsic apoptotic signaling pathway · negative regulation of viral release from host cell · negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process · regulation of double-strand break repair早幼粒细胞白血病蛋白是指可能的转录因子可能的转录因子(英语:Probable transcription factor PML),是一个由人类基因 PML 编码的抑癌蛋白。早幼粒细胞白血病蛋白可与下列蛋白质发生交互作用:

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