ERCC2

· ATP-dependent DNA helicase activity
· protein kinase activity
· protein binding
· ATP binding
· protein C-terminus binding
· DNA-dependent ATPase activity
· RNA polymerase II carboxy-terminal domain kinase activity
· 5'-3' DNA helicase activity
· metal ion binding
· protein N-terminus binding

· nucleus
· nucleoplasm
· holo TFIIH complex
· cytoplasm
· spindle
· cyclin-dependent protein kinase activating kinase holoenzyme complex

· nucleotide-excision repair, DNA damage removal
· response to hypoxia
· in utero embryonic development
· DNA repair
· transcription-coupled nucleotide-excision repair
· nucleotide-excision repair
· transcription from RNA polymerase I promoter
· transcription initiation from RNA polymerase I promoter
· transcription elongation from RNA polymerase I promoter
· termination of RNA polymerase I transcription
· transcription from RNA polymerase II promoter
· transcription initiation from RNA polymerase II promoter
· transcription elongation from RNA polymerase II promoter
· 7-methylguanosine mRNA capping
· protein phosphorylation
· apoptotic process
· induction of apoptosis
· response to oxidative stress
· chromosome segregation
· aging
· cell proliferation
· UV protection
· post-embryonic development
· gene expression
· viral reproduction
· virus-host interaction
· spinal cord development
· viral reproductive process
· extracellular matrix organization
· bone mineralization
· central nervous system myelin formation
· nucleotide-excision repair, DNA incision
· multicellular organism growth
· hair cell differentiation
· embryonic cleavage
· negative regulation of apoptotic process
· erythrocyte maturation
· positive regulation of DNA binding
· skin development
· small molecule metabolic process
· positive regulation of transcription, DNA-dependent
· positive regulation of transcription from RNA polymerase II promoter
· hair follicle maturation
· positive regulation of viral transcription

ERCC2 或 XPD是一种涉及转录偶联核苷酸切除修复的蛋白质。