雄激素受体

1E3G, 1GS4, 1T5Z, 1T63, 1T65, 1XJ7, 1XOW, 1XQ3, 1Z95, 2AM9, 2AMA, 2AMB, 2AO6, 2AX6, 2AX7, 2AX8, 2AX9, 2AXA, 2HVC, 2OZ7, 2PIO, 2PIP, 2PIQ, 2PIR, 2PIT, 2PIU, 2PIV, 2PIW, 2PIX, 2PKL, 2PNU, 2Q7I, 2Q7J, 2Q7K, 2Q7L, 2YHD, 2YLO, 2YLP, 2YLQ, 2Z4J, 3B5R, 3B65, 3B66, 3B67, 3B68, 3BTR, 3L3X, 3L3Z, 3RLJ, 3RLL, 3V49, 3V4A, 3ZQT, 4HLW· DNA binding · chromatin binding · sequence-specific DNA binding transcription factor activity · ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity · androgen receptor activity · receptor binding · androgen binding · protein binding · beta-catenin binding · transcription factor binding · zinc ion binding · enzyme binding · sequence-specific DNA binding · transcription regulatory region DNA binding · protein dimerization activity · androgen receptor binding· nucleus · nucleoplasm · cytoplasm · plasma membrane · axon · dendrite· regulation of systemic arterial blood pressure · transcription, DNA-dependent · transcription initiation from RNA polymerase II promoter · transport · signal transduction · cell-cell signaling · sex differentiation · cell death · cell proliferation · positive regulation of cell proliferation · male gonad development · gene expression · cell growth · male somatic sex determination · androgen receptor signaling pathway · intracellular receptor signaling pathway · prostate gland development · response to insulin stimulus · positive regulation of intracellular estrogen receptor signaling pathway · positive regulation of phosphorylation · negative regulation of apoptotic process · positive regulation of MAPK cascade · positive regulation of insulin-like growth factor receptor signaling pathway · negative regulation of integrin biosynthetic process · positive regulation of integrin biosynthetic process · positive regulation of transcription, DNA-dependent · positive regulation of transcription from RNA polymerase II promoter · positive regulation of transcription from RNA polymerase III promoter · regulation of developmental growth · organ formation · male genitalia morphogenesis · negative regulation of epithelial cell proliferation · regulation of catalytic activity · positive regulation of NF-kappaB transcription factor activity · protein oligomerization · activation of prostate induction by androgen receptor signaling pathway · morphogenesis of an epithelial fold · lateral sprouting involved in mammary gland duct morphogenesis · regulation of prostatic bud formation · prostate gland growth · prostate gland epithelium morphogenesis · epithelial cell differentiation involved in prostate gland development · tertiary branching involved in mammary gland duct morphogenesis · mammary gland alveolus development结构 / ECOD雄激素受体（英语：androgen receptor，简称为AR），亦被称为NR3C4（核受体亚家族3，C组，成员4）是一类核受体，当雄性激素睾酮或二氢睾酮在细胞质中与之结合后会使之激活继而转运进核内。雄激素受体与孕酮受体之间的关系很密切，高剂量的黄体制剂可阻断雄激素受体。雄激素受体的主要功能是作为调控基因表达的一种结合DNA的转录因子；然而雄激素受体也有其它方面的功能。受雄激素调控的基因在男性性表型的发育及维持中起到重要作用。注意：此处包括了那些只有微弱男性化效应（或抗男性化（如氧雄龙））的蛋白同化甾类（因为它们合成代谢效应也是通过激活雄激素受体而是显得）。Note: 21-Hydroxylase inhibitors may also affect androgen levels as they prevent metabolism of androgen steroid precursors.